Publikační činnost

2023

Alterations in lipidome profiles distinguish early-onset hyperuricemia, gout, and the effect of urate-lowering treatment; Kvasnička, A., Friedecký, D., Brumarová, R. et al.; Arthritis Res Ther 25, 234 (2023). https://doi.org/10.1186/s13075-023-03204-6

Selective pivot logratio coordinates for partial least squares discriminant analysis modelling with applications in metabolomics; Štefelová, N., de Sousa, J., Hron, K., Palarea-Albaladejo, J., Dobešová, D., Kvasnička, A., & Friedecký, D.; Stat, 12 (1), e592, 2023; https://doi.org/10.1002/sta4.592

Rapid and efficient LC-MS/MS diagnosis of inherited metabolic disorders: a semi-automated workflow for analysis of organic acids, acylglycines, and acylcarnitines in urine; Piskláková, Barbora, Friedecká, Jaroslava, Ivanovová, Eliška, Hlídková, Eva, Bekárek, Vojtěch, Prídavok, Matúš, Kvasnička, Aleš, Adam, Tomáš and Friedecký, David; Clinical Chemistry and Laboratory Medicine (CCLM), 2023. https://doi.org/10.1515/cclm-2023-0084

Vascular Damage and Glycometabolic Control in Older Patients with Type 2 Diabetes; Karasek D, Spurna J, Macakova D, Krystynik O, Kucerova V, Metabolites 2023, 13(3), 382; https://doi.org/10.3390/metabo13030382

Clinical lipidomics in the era of the big data; Kvasnička A, Najdekr L, Dobešová D, Piskláková B, Ivanovová E, Friedecký D, Clinical Chemistry and Laboratory Medicine (CCLM), 2022, 61(4), https://doi.org/10.1515/cclm-2022-1105

Non-altered incretin secretion in woman with impaired fasting plasma glucose in the early stage of pregnancy: a case control study; Krystyník O., Karasek D., Kahle M., Kubickova V., Macakova D., Cibickova L., Mraz M., Haluzik M., Diabetology and Metabolic Syndrome (2023) 15:12. (IF 5,395) https://doi.org/10.1186/s13098-023-00981-7

2022
From big data to better patient outcomes; Hulsen T, Friedecký D, Renz H, Melis E, Vermeersch P, Fernandez-Calle P, Clinical Chemistry and Laboratory Medicine (CCLM), 2022, 61(4), https://doi.org/10.1515/cclm-2022-1096

Altered Plasma, Urine, and Tissue Profiles of Sulfatides and Sphingomyelins in Patients with Renal Cell Carcinoma; Jirásko R, Idkowiak J, Wolrab D, Kvasnička A, Friedecký D, Polański K, Študentová H, Študent V, Melichar B, Holčapek M, Cancers, 2022, 14(19), 4622; https://doi.org/10.3390/cancers14194622.

Dynamics of acylcarnitines, hypoglycin A, méthylènecyclopropylglycine and their metabolites in a Kladruber stallion with atypical myopathy; Jahn P, Dobešová D, Brumarová R, Tóthová K, Kopecká A, Friedecký D, Veterinary Quarterly, 2022; (s. 1-12) https://doi.org/10.1080/01652176.2022.2126537

Specific gut bacterial and fungal microbiota pattern in the first half of pregnancy is linked to the development of gestational diabetes mellitus in the cohort including obese women; Vavrečková M, Galanová N, Kostovčík M, Krystýnek O, Ivanovová E, Roubalová R, Jirásková Zákostelská Z, Friedecký D, Friedecká J, Haluzík M, Karásek D, Kostovčíková K; Frontiers in Endocrinology (Clinical Diabetes section) 2022, (13: 970825) doi: 10. 3389/fendo.2022 .970825

Determination of Thrombogenicity Levels of Various Antiphospholipid Antibodies by a Modified Thrombin Generation Assay in Patients with Suspected Antiphospholipid Syndrome; Bradáčová P, Slavík L, Skoumalová A, Úlehlová J, Kriegová E, Manukyan G, Friedecký D, Piskláková B, Ullrychová J, Procházková J, Hluší A. International Journal of Molecular Sciences. 2022; 23(16):8973. https://doi.org/10.3390/ijms23168973

Biomarkers of Neurodegenerative Diseases: Biology, Taxonomy, Clinical Relevance, and Current Research Status; Koníčková D, Menšíková K, Tučková L, Hényková E, Strnad M, Friedecký D, Stejskal D, Matěj R, Kaňovský P, Biomedicines. 2022; 10(7):1760. https://doi.org/10.3390/biomedicines10071760

Metabolomic, Lipidomic and Proteomic Characterisation of Lipopolysaccharide-induced Inflammation Mouse Model; Puris E, Kouřil Š, Najdekr L, Auriola S, Loppi S, Korhonen P, Gómez-Budia M, Fricker G, Kanninen K M, Malm T, Friedecký D, Gynther M, Neuroscience 2022, (Vol. 496, pp. 165-178), https://doi.org/10.1016/j.neuroscience.2022.05.030

Combined Targeted and Untargeted Profiling of HeLa Cells Deficient in Purine De Novo Synthesis; Mádrová L, Součková O, Brumarová R, Dobešová D, Václavík J, Kouřil Š, de Sousa J, Friedecká J, Friedecký D, Barešová V, Zikánová M, Adam T, Metabolites. 2022 12, 241. https://doi.org/10.3390/metabo12030241

Lipidomic profiling of human serum enables detection of pancreatic cancer; Wolrab D, Jirásko R, Cífková E, Höring M, Mei D, Chocholoušková M, Peterka O, Idkowiak J, Hrnčiarová T, Kuchař L, Ahrends R, Brumarová R, Friedecký D, Vivo-Truyols G, Škrha P, Škrha J, Kučera R, Melichar B, Liebisch G, Burkhardt R, Wenk M, Cazenave-Gassiot A, Karásek P, Novotný I, Greplová K, Hrstka R, Holčapek M, Nature Communications. 2022 13(1). https://doi.org/10.1038/s41467-021-27765-9

Lipidomic and metabolomic analysis reveals changes in biochemical pathways for non-small cell lung cancer tissues; Cífková E, Brumarová R, Ovčačíková M, Dobešová D, Mičová K, Kvasnička A, Vaňková Z, Šiller J, Sákra L, Friedecký D, Holčapek M, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2022 (Vol. 1867, Issue 2, p. 159082). Elsevier BV. https://doi.org/10.1016/j.bbalip.2021.159082

Circulating levels of WISP-1 (Wnt1-inducible signaling pathway protein 1) and other selected adipokines in children with inflammatory bowel disease; Karaskova E., Kucerova V., Velganova-Veghova M., and col.; Physiological research / Academia Scientiarum Bohemoslovaca. April 2022. https://doi.org/10.33549/physiolres.934854 (IF 1,88)

Adiponectin, A-FABP and FGF-19 Levels in Women with Early Diagnosed Gestational Diabetes; Karasek D., Krystynik O., Kucerova V., and col.,J.; Clin. Med. 2022, 11, 2417. https://doi.org/10.3390/jcm11092417 (IF 5,583)

Bone metabolism parameters and their relation to cytogenetics in multiple myeloma; Krhovska P, Pika T., Petrova J., Proskova J. , Balcarkova J., Zapletalova J., Bacovsky J., Minarik J., Eur J; Haematol. 2022 Jul; 109(1):75-82; https://doi.org/10.1111/ejh.13771

2021
GM3 Ganglioside Linked to Neurofibrillary Pathology in a Transgenic Rat Model for Tauopathy; Olešová, D., Majerová, P., Hájek, R., Piešťanský, J., Brumarová, R., Michalicová, A., Jurkanin, B., Friedecký, D., Kováč, A. Int. J. Mol. Sci. 2021, 22, 12581. https://doi.org/10.3390/ijms222212581

Evaluation of the Determination of Dabigatran, Rivaroxaban, and Apixaban in Lupus Anticoagulant-Positive Patients; Úlehlová J, Piskláková B, Ivanovová E, Procházková J, Bradáčová P, Kvasnička A, Friedecký D, Slavík L, Diagnostics 2021; 11(11):2027. https://doi.org/10.3390/diagnostics11112027

Plasma Short-Chain Fatty Acids and Their Derivatives in Women with Gestational Diabetes Mellitus; Ivanovová E, Piskláková B, Friedecká J, Krystyník O, Friedecký D, Karásek D. Separations. 2021; 8(10):188. https://doi.org/10.3390/separations8100188

Vliv novorozeneckého screeningu a časného dietního režimu na klinické výsledky pacientů s deficitem 3-hydroxyacyl-CoA dehydrogenázy s dlouhým řetězcem a deficitem acyl-CoA dehydrogenázy se středním řetězcem - retrospektivní celostátní studie; Rücklová K, Hrubá E, Pavlíková M, Hanák P, Farolfi M, Chrastina P, Vlášková H, Kousal B, Smolka V, Foltenová H, Adam T, Friedec

SLIDE-Novel Approach to Apocrine Sweat Sampling for Lipid Profiling in Healthy Individuals; Kvasnička A, Friedecký D, Tichá A, Hyšpler R, Janečková H, Brumarová R, Najdekr L, Zadák Z, Int. J. Mol. Sci. 2021;22: 8054. https://doi.org/10.3390/ijms22158054

Novel LC-MS tools for diagnosing inborn errors of metabolism; Ivanovová E, Piskláková B, Dobešová D, Kvasnička A, Friedecký D, Microchem J. 2021 Jul; 170, 106654. https://doi.org/10.1016/j.microc.2021.106654

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice; Puris E, Kouřil Š, Najdekr L, Loppi S, Korhonen P, Kanninen KM, Malm T, Koistinaho J, Friedecký D, Gynther M, Sci Rep. 2021 Jun 22;11(1):13076. https://doi.org/10.1038/s41598-021-92602-4

Retinal oxygen saturation is associated with HbA1c but not with short-term diabetes control, internal environment, smoking and mild retinopathy – ROXINEGLYD study; Mlcak P., Chlup R., Kucerova V., and col.; Acta Opthalmologica 2021. https://doi.org/10.1111/aos.14853 (IF 3,153)

Role of adipose tissue in inflammatory Bowel disease; Karaskova E., Velganova-Veghova M., Kucerova V., and col.; International Journal of Molecular Sciences 2021, 22, 4226. https://doi.org/0.3390/ijms22084226 (IF 4,556)

Hypertriglyceridemic Waist in Patients with Type 2 Diabetes: Its Relationship to Selected Markers of Vascular Damage; Karasek D., Spurna J., Macakova D., Cibickova L., Krystynik O., Kucerova V., Ulehlova J., Slavik L.; Metabolic Syndrome And Related Disorders, 2021, Volume XX, Number XX. https://doi.org/10.1089/met.2021.0019 (IF 1,734)

Adipocytokines in Graves' orbitopathy and the effect of high-dose corticosteroids; Schovanek J., Krupka M., Cibickova L., Karhanova M., Reddy S., Kucerova V., Frysak Z., Karasek D.; The Adipocyte journal, January, 2021. https://doi.org/10.1080/21623945.2021.1980258 (IF 4,534)

A rare case of bifocal, extramedullary and hyposecretory relapse of multiple myeloma; Minarik J, Szotkowski T., Hrbek J, Krhovska P, Buriankova E, Proškova J., Pika T, Bacovsky J.; Clin Casep. 2021, 9:e04570; https://doi.org/10.1002/ccr3.4570

2020–1999
A newborn screening approach to diagnose 3-hydroxy-3-methylglutaryl-CoA lyase deficiency; Václavík J, Mádrová L, Kouřil Š, de Sousa J, Brumarová R, Janečková H, Jáčová J, Friedecký D, Knapková M, Kluijtmans LAJ, Grünert SC, Vaz FM, Janzen N, Wanders RJA, Wevers RA, Adam T. ; JIMD Rep. 2020 Apr 14; 54(1):79-86. https://doi.org/10.1002/jmd2.12118 eCollection 2020 Jul.

Global DNA methylation in rats´ liver is not affected by hypercholesterolemic diet; Jurčíková-Novotná L, Mrázová L, Mičová K, Friedecký D, Hubáček JA, Poledne R.; Physiol Res. 2020 Apr 30; 69(2):347-252. https://doi.org/10.33549/physiolres.934313 Epub 2020 Mar 23.

Cellwise outlier detection and biomarker identification in metabolomics based on pairwise log ratios; Walach J, Filzmoser P, Kouřil Š, Friedecký D, Adam T.; J Chemom. 2020 Jan; 34(1):e3182. https://doi.org/10.1002/cem.3182 Epub 2019 Dec 2.

CROP: correlation-based reduction of feature multiplicities in untargeted metabolomic data; Kouřil Š, de Sousa J, Václavík J, Friedecký D, Adam T.; Bioinformatics. 2020 May 1; 36(9):2941-2942. https://doi.org/10.1093/bioinformatics/btaa012.

The Malacca Strait separates distinct faunas of poorly-flying Cautires net-winged beetles; Jiruskova A, Motyka M, Bocek M, Bocak L. 2019; PeerJ 7:e6511 https://doi.org/10.7717/peerj.6511

Circulating levels of selected adipokines in woman with gestational diabetes and type 2 diabetes; Karasek D., Krystynik O., Goldmannova, Kubickova V., Cibickova L., Schovanek J.; Journal of applied Biomedicine 18:54-60, 2020. https://doi.org/10.32725/jab.2020.007 (IF 1.922).

Association of Pigment Epithelium Derived Factor With von Willebrand Factor and Plasminogen Activator Inhibitor 1 in Patients With type 2 Diabetes; Karasek D., Spurna J., Kubickova V., Krystynik O., Cibickova L., Schovanek J., Goldmannova D.; Physiological research 68: 409 – 418,2019. https://doi.org/10.33549/physiolres.934013 (IF 1.701).

Relationship of Selected Adipokines with Markers of Vascular Damage in Patients with Type 2 Diabetes; Spurna J., Karasek D., Kubickova V., Goldmannova D., Krystynik O., Schovanek J., Zadrazil J.; Metabolic Syndrome and Related Disorders 16 (5) May 2018. https://doi.org/10.1089/met.2017.0179 (IF 1,744)

Association of serum adipocyte fatty acid-binding protein and apolipoprotein B /apolipoprotein A1 ratio with intima media thickness of common carotid artery in dyslipidemic patiens; Orsag J., Karasek D., Halenka M., Zadrazil J., Vaverkova H., Spurna J., Kubickova V., Lukes J.; Biomedical papers of the Medical Faculty of the University Palacky September 2018. https://doi.org/10.5507/bp.2018.043 (IF 1,087)

Pigment epithelium derived factor and C1Q/TNF-related protein 9 in patients with type 2 diabetes: relationship to metabolic syndrome and vascular damage; Karasek D., Spurna J., Kubickova V., Cibickova L., Golgmannova D.; Atherosclerosis 275 August 2018. https://doi.org/10.1016/j.atherosclerosis.2018.06.384 (IF 4,467)

Potential utilization of neopterin measurements in the assessment of pyrexia in metastatic melanoma treated with combined targeted therapy: a case report; Bartoušková M., Hrouzková M., Čtvrtlík F., Petrová P., Rušarová N., Kučerová K., Vernerová A., Melichar B., Študentová H.; Pteridines 2020;31, 151-157; https://doi.org/10.1515/pteridines-2020-0009

The effect of Tobacco Smoking and Smoking Cessation on Urinal miRNAs in a Pilot Study; Zdenka Navratilova, Stanislav Losse, Pavla Petrova, Katerina Sikorova, Alzbeta Chabronova, Martin Petrek ; Life 2020,10,191; http://dx.doi.org/10.3390/life10090191

A newborn screening approach to diagnose 3-hydroxy-3-methylglutaryl-CoA lyase deficiency; Václavík J, Mádrová L, Kouřil Š, de Sousa J, Brumarová R, Janečková H, Jáčová J, Friedecký D, Knapková M, Kluijtmans LAJ, Grünert SC, Vaz FM, Janzen N, Wanders RJA, Wevers RA, Adam T. ; JIMD Rep. 2020 Apr 14; 54(1):79-86. https://doi.org/10.1002/jmd2.12118 eCollection 2020 Jul.

Možnosti laboratorní diagnostiky novorozenecké sepse; Baštan A., Prošková J.; Labor Aktuell 2020, No. 1, p. 4-9; www.labor-aktuell.cz

The relationship between serum levels of selected biomarkers of bone marrow microenvironment and the activity of multiple myeloma; J. Proskova, P. Krhovska, Z. Hermanova, P. Petrova, T. Pika, J. Bacovsky, J. Minarik; Clinica Chimica Acta 493, S138-S139 · June 2019; https://doi.org/10.1016/j.cca.2019.03.293

Adipocyte fatty acid-binding protein in patients with type 2 diabetes: Its relationship to vascular damage; Kubíčková v., Karásek D., Spurná J., Krystynik O., Petrova p., Cibíčková L.; Clinica Chimica Acta, June 2019, 493:S309; https://doi.org/10.1016/j.cca.2019.03.637

Characterization of five CHASE-containing histidine kinase receptors from Populus × canadensis cv. Robusta sensing isoprenoid and aromatic cytokinins; Jaworek, P., Tarkowski, P., Hluska, T., Kouřil, Š., Vrobel, O., Nisler, J., & Kopečný, D., 2019; Planta, 251(1), 1. https://doi.org/10.1007/s00425-019-03297-x

Occurrence and biosynthesis of cytokinins in poplar. Jaworek, P., Kopečný, D., Zalabák, D., Šebela, M., Kouřil, Š., Hluska, T., Končitíková, R., Podlešáková, K., & Tarkowski, P., 2019; Planta, 250(1), 229–244. https://doi.org/10.1007/s00425-019-03152-z

Hodnocení kostního obratu a významu deficitu vitaminu D u pacientů s myelofibrózou; Palová M., Szotkowski T., Hluší A., Navrátilová J., Divoká M., Papajík T., Petrová P., Prošková J.1; Transfuze Hematol. dnes, 25, 2019, No. 2, p. 159–167

Bayesian multiple hypotheses testing in compositional analysis of untargeted metabolomic data; de Sousa J, Vencálek O, Hron K, Václavík J, Friedecký D, Adam T.; Anal Chim Acta. 2020 Feb 8; 1097:49-61. https://doi.org/10.1016/j.aca.2019.11.006 Epub 2019 Nov 16.

Evaluation of the DOAC-Stop Procedure by LC-MS/MS Assays for Determining the Residual Activity of Dabigatran, Rivaroxaban, and Apixaban; Slavík L, Jáčová J, Friedecký D, Úlehlová J, Tauber Z, Procházková J, Hlusi A, Pálová M.; Clin Appl Thromb Hemost. 2019 Jan-Dec; 25:1076029619872556. https://doi.org/10.1177/1076029619872556.

Urease-immobilized magnetic microparticles in urine sample preparation for metabolomic analysis by gas chromatography-mass spectrometry; Jáčová J, Jořenek M, Pospíšková K, Najdekr L, Zajoncová L, Friedecký D, Adam T.; J Chromatogr A. 2019 Nov 8; 1605:360355. https://doi.org/10.1016/j.chroma.2019.07.009. Epub 2019 Jul 10.

Epidemiology of rare diseases detected by newborn screening in the Czech Republic; David J, Chrastina P, Pešková K, Kožich V, Friedecký D, Adam T, Hlídková E, Vinohradská H, Novotná D, Hedelová M, Al Taji E, Holubová A, Skalická V, Macek M, Gaillyová R, Votava F.; Cent Eur J Public Health. 2019 Jun; 27(2):153-159. https://doi.org/10.21101/cejph.a5441.

White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality [Reakce bílé tukové tkáně obézních myší na omezení příjmu kyslíku v prostředí při termoneutralitě]: Hoevenaars FPM, Keijer J, van der Stelt I, Duivenvoorde LPM, Herreman L, van Nes R, Friedecký D, Hegeman MA, van Schothorst EM.; Genes (Basel). 2019 May 10; 10(5):359. https://doi.org/10.3390/genes10050359.

Impact of sample dimensionality on orthogonality metrics in comprehensive two-dimensional separations [Vliv dimenzionality vzorku na metriky ortogonality v komplexních dvourozměrných separacích]; Jáčová J, Gardlo A, Dimandja JD, Adam T, Friedecký D.; Anal Chim Acta. 2019 Aug 8; 1064:138-149. https://doi.org/10.1016/j.aca.2019.03.018. Epub 2019 Mar 12.

Mass spectrometric analysis of purine de novo biosynthesis intermediates; Mádrová L, Krijt M, Barešová V, Václavík J, Friedecký D, Dobešová D, Součková O, Škopová V, Adam T, Zikánová M.; PLoS One. 2018 Dec 10; 13(12):e0208947. https://doi.org/10.1371/journal.pone.0208947. eCollection 2018.

Human White Adipose Tissue Metabolome: Current Perspective; Kučera J, Spáčil Z, Friedecký D, Novák J, Pekař M, Bienertová-Vašků J.; Obesity (Silver Spring). 2018 Dec; 26(12):1870-1878. https://doi.org/10.1002/oby.22336 Epub 2018 Oct 28.

Multianalytické stanovení NOACs pomocí LC-MS/MS a srovnání s funkčními koagulačními testy; Slavík L, Lukeš J, Frýdecký D, Žanelová M, Němcová M, Úlehlová J, Procházková J, Hlusi A, Pálová M, Václavík J.; Clin Lab. 2018 Oct 1; 64(10):1611-1621. https://doi.org/10.7754/clin.lab.2018.180335.

Newborn foal with atypical myopathy; Karlíková R, Široká J, Mech M, Friedecký D, Janečková H, Mádrová L, Hrdinová F, Drábková Z, Dobešová O, Adam T, Jahn P.; J Vet Intern Med. 2018 Sep; 32(5):1768-1772. https://doi.org/10.1111/jvim.15236. Epub 2018 Sep 14.

Radio-sensitizing effects of VE-821 and beyond: Distinct phosphoproteomic and metabolomic changes after ATR inhibition in irradiated MOLT-4 cells; Šalovská B, Janečková H, Fabrik I, Karlíková R, Čecháková L, Ondrej M, Link M, Friedecký D, Tichý A.; PLoS One. 2018 Jul 12; 13(7):e0199349. https://doi.org/10.1371/journal.pone.0199349 eCollection 2018.

Critical evaluation of colon submucosal microdialysis in awake, mobile rats; Cibicek N., Ehrmann J., Proskova J., Vecera P.; LoS ONE 2018 Jan 11;13(1); https://doi.org/10.1371/journal.pone.0191041

Serum IL-6 in combination with synovial IL-6/CRP shows excellent diagnostic power to detect hip and knee prosthetic joint infection; Jiri Gallo, MD, PhD; Michal Svoboda; Jana Zapletalova; Jitka Proskova; Jarmila Juranova; PLoS ONE 2018; 13(6); https://doi.org/10.1371/journal.pone.0199226

Electrocatalytic artificial carbonylation assay for observation of human serum albumin inter-individual properties; Jan Vacek, Marika Svrckova, Martina Zatloukalova, David Novak, Jitka Proskova, Katerina Langova, Dana Galuszkova, Jitka Ulrichova; Analytical Biochemistry 550 (2018) 137–143; https://doi.org/10.1016/j.ab.2018.04.025

Neonatal screening in the Czech Republic: increased prevalence of selected diseases in low birthweight neonates. David J., Chrastina P., Vinohradska H., Al Taji E., Holubova A., Hlidkova E., Kozich V., Votava F.; Eur J Pediatr. 2018 Nov; 177(11):1697-1704. https://doi.org/10.1007/s00431-018-3230-y. Epub 2018 Aug 22.PMID: 30136145

Structural elucidation of novel biomarkers of known metabolic disorders based on multistage fragmentation mass spectra; Václavík J, Coene KLM, Vrobel I, Najdekr L, Friedecký D, Karlíková R, Mádrová L, Petsalo A, Engelke UFH, van Wegberg A, Kluijtmans LAJ, Adam T, Wevers RA.; J Inherit Metab Dis. 2018 May; 41(3):407-414. https://doi.org/10.1007/s10545-017-0109-4. Epub 2017 Nov 14.

Metabolic status of CSF distinguishes rats with tauopathy from controls; Karlíková R, Mičová K, Najdekr L, Gardlo A, Adam T, Majerová P, Friedecký D, Kováč A.; Alzheimers Res Ther. 2017 Sep 21; 9(1):78. https://doi.org/10.1186/s13195-017-0303-5.

Toll-Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris suum-induced Allergic Asthma in Nonhuman Primates; Camateros P, Kanagaratham C, Najdekr L, Holub D, Vrbkova J, Coté L, Fournier J, Gourdon J, Creery D, Olivenstein R, Kopriva F, Adam T, Friedecký D, Džubák P, Hajdúch M, Radzioch D. ; Am J Respir Cell Mol Biol. 2018 Jan; 58(1):55-65. https://doi.org/10.1165/rcmb.2017-0184oc.

Sample-independent approach to normalize two-dimensional data for orthogonality evaluation using whole separation space scaling; Jáčová J, Gardlo A, Friedecký D, Adam T, Dimandja JD. ; J Chromatogr A. 2017 Aug 18; 1511:1-8. https://doi.org/10.1016/j.chroma.2017.06.076. Epub 2017 Jul 3.

Novel sulphur-containing imatinib metabolites found by untargeted LC-HRMS analysis; Vrobel I, Friedecký D, Faber E, Najdekr L, Mičová K, Karlíková R, Adam T.; Eur J Pharm Sci. 2017 Jun 15; 104:335-343. https://doi.org/10.1016/j.ejps.2017.04.014. Epub 2017 Apr 20.

Metabolic Response of Visceral White Adipose Tissue of Obese Mice Exposed for 5 Days to Human Room Temperature Compared to Mouse Thermoneutrality; van der Stelt I, Hoevenaars F, Široká J, de Ronde L, Friedecký D, Keijer J, van Schothorst E.; Front Physiol. 2017 Mar 23; 8:179. https://doi.org/10.3389/fphys.2017.00179. eCollection 2017.

Influence of Mass Resolving Power in Orbital Ion-Trap Mass Spectrometry-Based Metabolomics (Vliv rozlišovací schopnosti v hmotnostní spektrometrii založené na orbitální iontové pasti); Najdekr L, Friedecký D, Tautenhahn R, Pluskal T, Wang J, Huang Y, Adam T.; Anal Chem. 2016 Dec 6; 88(23):11429-11435. https://doi.org/10.1021/acs.analchem.6b02319. Epub 2016 Nov 23.

Equine atypical myopathy: A metabolic study; Karlíková R, Široká J, Jahn P, Friedecký D, Gardlo A, Janečková H, Hrdinová F, Drábková Z, Adam T.; Vet J. 2016 Oct; 216:125-32. https://doi.org/10.1016/j.tvjl.2016.07.015 Epub 2016 Jul 29

Metabolite Profiling of the Plasma and Leukocytes of Chronic Myeloid Leukemia Patients; Karlíková R, Široká J, Friedecký D, Faber E, Hrdá M, Mičová K, Fikarová I, Gardlo A, Janečková H, Vrobel I, Adam T.; J Proteome Res. 2016 Sep 2; 15(9):3158-66. https://doi.org/10.1021/acs.jproteome.6b00356. Epub 2016 Aug 9.

Ultrafast Online SPE-MS/MS Method for Quantification of 3 Tyrosine Kinase Inhibitors in Human Plasma; Vrobel I, Janečková H, Faber E, Bouchalová K, Mičová K, Friedecký D, Adam T.; Ther Drug Monit. 2016 Aug; 38(4):516-24. https://doi.org/10.1097/ftd.0000000000000309.

Dr. Jekyll a pan Hyde: zvláštní případ 5-ethynyl-2′-deoxyuridinu a 5-ethynyl-2′-deoxycytidinu; Ligasová A, Liboska R, Friedecký D, Mičová K, Adam T, Oždian T, Rosenberg I, Koberna K.; Open Biol. 2016 Jan; 6(1):150172. https://doi.org/10.1098/rsob.150172.

Detailed study of imatinib metabolization using high-resolution mass spectrometry; Friedecký D, Mičová K, Faber E, Hrdá M, Široká J, Adam T.; J Chromatogr A. 2015 Aug 28; 1409:173-81. https://doi.org/10.1016/j.chroma.2015.07.033. Epub 2015 Jul 13.

Citrulline as a biomarker of gastrointestinal toxicity in patients with rectal carcinoma treated with chemoradiation; Zezulová M, Bartoušková M, Hlídková E, Adam T, Kujovská Krčmová L, Červinková B, Solichová D, Zlevorová M, Cwiertka K, Friedecký D, Vrána D, Melichar B.; Clin Chem Lab Med. 2016 Feb; 54(2):305-14. https://doi.org/10.1515/cclm-2015-0326

A lower dosage of imatinib is sufficient to maintain undetectable disease in patients with chronic myeloid leukemia with long-term low-grade toxicity of the treatment; Faber E, Divoká M, Skoumalová I, Novák M, Marešová I, Mičová K, Friedecký D, Adam T, Jarošová M, Indrák K.; Leuk Lymphoma. 2016 Feb; 57(2):370-375. https://doi.org/10.3109/10428194.2015.1056184 Epub 2015 Jun 22.

Oxidized phosphatidylcholines suggest oxidative stress in patients with medium-chain acyl-CoA dehydrogenase deficiency; Najdekr L, Gardlo A, Mádrová L, Friedecký D, Janečková H, Correa ES, Goodacre R, Adam T.; Talanta. 2015 Jul 1; 139:62-6. https://doi.org/10.1016/j.talanta.2015.02.041. Epub 2015 Mar 4.

A Fatal Combination: A Thymidylate Synthase Inhibitor with DNA Damaging Activity; Ligasová A, Strunin D, Friedecký D, Adam T, Koberna K.; PLoS One. 2015 Feb 11; 10(2):e0117459. https://doi.org/10.1371/journal.pone.0117459 eCollection 2015.

Untargeted metabolomic analysis of urine samples in the diagnosis of some inherited metabolic disorders; Janeckova H, Kalivodova A, Najdekr L, Friedecky D, Hron K, Bruheim P, Adam T.; Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Dec; 159(4):582-5. https://doi.org/10.5507/bp.2014.048. Epub 2014 Nov 7.

Fenretinide Prevents Inflammation and Airway Hyperresponsiveness in a Mouse Model of Allergic Asthma; Kanagaratham C, Kalivodová A, Najdekr L, Friedecký D, Adam T, Hajduch M, De Sanctis JB, Radzioch D.; Am J Respir Cell Mol Biol. 2014 Dec; 51(6):783-92. https://doi.org/10.1165/rcmb.2014-0121OC

Analysis of cytokinin nucleotides by capillary zone electrophoresis with diode array and mass spectrometric detection in a recombinant enzyme in vitro reaction; Béres T, Gemrotová M, Tarkowski P, Ganzera M, Maier V, Friedecký D, Dessoy MA, Wessjohann LA, Spíchal L, Strnad M, Doležal K.; Anal Chim Acta. 2012 Nov 2; 751:176-81. https://doi.org/10.1016/j.aca.2012.08.049. Epub 2012 Sep 5.

A significant proportion of patients with chronic myeloid leukemia and suboptimal response according to European Leukemia Net criteria have excellent prognosis without treatment change; Rohon P, Faber E, Divoka M, Rozmanova S, Friedecky D, Jarosova M, Indrak K.; Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2013 Jun; 157(2):181-8. https://doi.org/10.5507/bp.2011.059. Epub 2011 Nov 30.

High lapatinib plasma levels in breast cancer patients: risk or benefit?; Čížková M, Bouchalová K, Frýdecký D, Polynková A, Janoštáková A, Radová L, Cwiertka K, Trojanec R, Zezulová M, Zlevorová M, Hajduch M, Melichar B.; Tumori. 2012 Jan-Feb; 98(1):162-5. https://doi.org/10.1177/030089161209800123

Isotope dilution direct injection mass spectrometry method for determination of four tyrosine kinase inhibitors in human plasma; Mičová K, Friedecký D, Faber E, Adam T.; Talanta. 2012 May 15; 93:307-13. https://doi.org/10.1016/j.talanta.2012.02.038 Epub 2012 Feb 22.

Imatinib trough plasma levels do not correlate with the response to therapy in patients with chronic myeloid leukemia in routine clinical setting; Faber E, Friedecký D, Mičová K, Rožmanová S, Divoká M, Jarošová M, Indrák K, Adam T.; Ann Hematol. 2012 Jun; 91(6):923-9. https://doi.org/10.1007/s00277-011-1394-x Epub 2012 Jan 11.

Targeted metabolomic analysis of plasma samples for the diagnosis of herherited metabolic disorders; Janečková H, Hron K, Wojtowicz P, Hlídková E, Barešová A, Friedecký D, Zídková L, Hornik P, Behúlová D, Procházková D, Vinohradská H, Pešková K, Bruheim P, Smolka V, Sťastná S, Adam T. ; J Chromatogr A. 2012 Feb 24; 1226:11-7. https://doi.org/10.1016/j.chroma.2011.09.074 Epub 2011 Oct 4.

Lapatinib in breast cancer - the predictive significance of HER1 (EGFR), HER2, PTEN and PIK3CA genes and lapatinib plasma level assessment; Bouchalová K, Čížková M, Cwiertka K, Trojanec R, Friedecky D, Hajduch M.; Biomed Pap Med Fac Univ Palacký Olomouc Czech Repub. 2010 Dec; 154(4):281-8. https://doi.org/10.5507/bp.2010.043.

Flow injection analysis vs. ultra high performance liquid chromatography coupled with tandem mass spectrometry for determination of imatinib in human plasma; Mičová K, Friedecký D, Faber E, Polýnková A, Adam T.; Clin Chim Acta. 2010 Dec 14; 411(23-24):1957-62. https://doi.org/10.1016/j.cca.2010.08.014. Epub 2010 Aug 13.

Oligodendroglia from ADSL-deficient patient produce SAICAribotide and SAMP; Zídková L, Krijt J, Sládková J, Hlobilková A, Magner M, Zikánová M, Kmoch S, Friedecký D, Zeman J, Elleder M, Adam T.; Mol Genet Metab. 2010 Oct-Nov; 101(2-3):286-8. doi: https://doi.org/10.1016/j.ymgme.2010.06.014. Epub 2010 Jun 25.

Imatinib dose escalation in two patients with chronic myeloid leukemia, with low trough imatinib plasma levels measured at various intervals from the beginning of therapy and with suboptimal treatment response, leads to the achievement of higher plasma levels and major molecular response; Faber E, Friedecký D, Micová K, Divoká M, Katrincsáková B, Rozmanová S, Jarosová M, Indrák K, Adam T.; Int J Hematol. 2010 Jun; 91(5):897-902. https://doi.org/10.1007/s12185-010-0576-y Epub 2010 May 1.

Capillary electrophoresis determination of thiopurine methyl transferase activity in erythrocytes; Tomkova J, Friedecky D, Polynkova A, Adam T.; J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jul 1; 877(20-21):1943-5. https://doi.org/10.1016/j.jchromb.2009.05.005. Epub 2009 May 13.

ITPase activity in dry blood spots is comparable with that in fresh erythrocytes; Tomková J, Friedecky D, Vyskočilová P, Adam T.; Nucleosides Nucleotides Nucleic Acids. 2008 Jun; 27(6):656-60. https://doi.org/10.1080/15257770802143897.

Determination of ITPase activity by capillary electrophoresis; Friedecky D, Tomkova J, Adam T.; Clin Chem. 2007 Jun; 53(6):1164-5. https://doi.org/10.1373/clinchem.2007.086058.

Capillary electrophoretic method for nucleotide analysis in cells: Application on inherited metabolic disorders; Friedecký D, Tomková J, Maier V, Janošťáková A, Procházka M, Adam T.; Electrophoresis. 2007 Feb; 28(3):373-80. https://doi.org/10.1002/elps.200600262

Synthesis and Mass Spectrometric Fragmentation Characteristics of Imidazole Ribosides–Analogs of Intermediates of Purine De Novo Synthetic Pathway; Vyskocilová P, Hornik P, Friedecký D, Frycák P, Lemr K, Adam T.; Nucleosides Nucleotides Nucleic Acids. 2006; 25(9-11):1237-40. https://doi.org/10.1080/15257770600894691

Analysis of intracellular nucleotides by capillary electrophoresis-mass spectrometry; Friedecký D, Bednár P, Procházka M, Adam T.; Nucleosides Nucleotides Nucleic Acids. 2006; 25(9-11):1233-6. https://doi.org/10.1080/15257770600894667.

Analysis of aminoimidazole ribosides by capillary electrophoresis — Diagnosing defects in second part of purine biosynthetic pathway; Horník P, Vyskocilová P, Friedecký D, Janostáková A, Adamová K, Adam T.; Clin Chim Acta. 2007 Feb; 376(1-2):184-9. https://doi.org/10.1016/j.cca.2006.08.020 Epub 2006 Sep 29.

Diagnosing AICA-ribosiduria by capillary electrophoresis; Horník P, Vyskocilová P, Friedecký D, Adam T.; J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Oct 20; 843(1):15-9. https://doi.org/10.1016/j.jchromb.2006.05.020 Epub 2006 Jun 23.

Analytical derivatization-a tool for determination of orotic acid; Husková R, Barták P, Cáp L, Friedecký D, Adam T.; J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jan 25; 799(2):303-9. https://doi.org/10.1016/j.jchromb.2003.10.068.

High-throughput capillary electrophoretic method for determination of total aminothiols in plasma and urine; Lochman P, Adam T, Friedecký D, Hlídková E, Skopková Z.; Electrophoresis. 2003 Apr; 24(7-8):1200-7. https://doi.org/10.1002/elps.200390154.

Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow; Adam T, Lochman P, Friedecký D.; J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Feb 15; 767(2):333-40. https://doi.org/10.1016/S1570-0232(01)00591-8

Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: a selective approach; Friedecký D, Adam T, Barták P.; Electrophoresis. 2002 Feb; 23(4):565-71. https://doi.org/10.1002/1522-2683(200202)23:4%3C565::aid-elps565%3E3.0.co;2-s

Mass Spectrometry for Analysis of Purine and Pyrimidine Compounds; Lemr K, Adam T, Frycák P, Friedecký D; Adv Exp Med Biol. 2000; 486:399-403. https://doi.org/10.1007/0-306-46843-3_76

Fast analysis of antibacterial isothiazolones by capillary electrophoresis; Barták P, Bednár P, Friedecký D, Haviger A, Sevcík J.; J Chromatogr B Biomed Sci Appl. 2001 Jul 15; 758(2):323-5. https://doi.org/10.1016/S0378-4347(01)00198-0.

Kapilární elektroforéza pro detekci dědičných poruch purinového a pyrimidinového metabolismu; Adam T, Friedecký D, Fairbanks LD, Ševčík J, Barták P.; Clin Chem. 1999 Dec; 45(12):2086-93.